A role for antimicrobial peptides in intestinal microsporidiosis
نویسندگان
چکیده
منابع مشابه
Antimicrobial peptides in innate intestinal host defence.
Precursors of alpha-defensin peptides require activation for bactericidal activity. In mouse small intestine, matrilysin colocalized with alpha-defensins (cryptdins) in Paneth cell granules, and in vitro it cleaved the pro segment from cryptdin precursors. Matrilysin-deficient (MAT−/−) mice lacked mature cryptdins and accumulated precursor molecules. Intestinal peptide preparations from MAT−/− ...
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In the last two decades, the scientific community has recognized the Microsporidia importance and associated it with serious infections in immunocompromised patients.1 Since its discovery in 1857, there was controversies in its phylogenetic classification, being recently classified as fungi.1,2 There have been described 150 genera and over 1300 species. Eight genera are described in human hosts...
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Milk proteins provide a natural source of bioactive peptides with potential health benefits and applications in the food industry. The release of these peptides from milk proteins is achieved either by hydrolysis using digestive proteases or by lactic acid bacteria fermentation. Peptides, particularly those derived from milk proteins, can exert a wide range of nutritional, functional and biolog...
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Center for Inflammatory Bowel Diseases; Division of Digestive Diseases, David Geffen School of Medicine, The University of California Los Angeles, Los Angeles, CA Corresponding author: Hon Wai Koon, Ph.D. Center for Inflammatory Bowel Diseases, MRL 1519, 675 Charles E. Young Drive South, The University of California Los Angeles, Los Angeles, CA 90095, U.S.A. Tel: 310-825-9742 Email: hkoon@medne...
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ژورنال
عنوان ژورنال: Parasitology
سال: 2008
ISSN: 0031-1820,1469-8161
DOI: 10.1017/s0031182008005313